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Our approach · Medical domains

Four domains of advanced medicine.

Strategic categories — not mutually exclusive medical classifications. A single patient’s pathway may involve several.

01

Complex & specialized care

Complex procedures and medical interventions requiring highly specialized expertise, infrastructure or equipment.

Cardiac surgeryNeurosurgeryOrgan transplantationComplex reconstructive surgeryTreatment after severe trauma or congenital abnormalitiesOther highly specialized surgical interventions

Why it matters for access

These interventions depend on rare teams and facilities. Where none exist locally, patients face the cost and logistics of treatment elsewhere.

02

Regenerative & advanced therapies

Therapeutic approaches designed to repair, replace or modify biological structures and functions.

Tissue engineeringCell-based therapiesGene therapiesRegenerative medicineAdvanced tissue reconstruction

Why it matters for access

Many of these therapies are available only in a few centers and can be very expensive. Because some are still innovative or experimental, they are reviewed with particular care.

03

Precision & personalized medicine

Medical approaches adapted to the biological, genetic and clinical characteristics of individual patients.

Targeted therapiesPrecision oncologySpecialized treatment of rare diseasesGenetically informed treatment strategiesIndividually adapted therapeutic approaches

Why it matters for access

Matching the right therapy to the right patient often requires specialized testing and expertise that is unevenly distributed.

04

Advanced diagnostics & medical technologies

Specialized technologies used to diagnose complex conditions or enable advanced medical treatment.

Advanced medical imagingGenetic sequencing for diagnostic purposesSpecialized medical devicesAdvanced interventional technologiesTechnologies supporting complex reconstruction

Why it matters for access

A precise diagnosis is often the first barrier. Where a diagnosis is itself part of the medical pathway, the lack of one never disqualifies an applicant.

An illustration

How domains combine

A hypothetical pathway — not a real case — showing how a single patient can cross several domains.

  1. Advanced diagnostics & technologies

    Advanced imaging and genetic sequencing identify a complex congenital condition.

  2. Complex & specialized care

    A specialist center performs the necessary reconstructive or cardiac procedure.

  3. Regenerative & advanced therapies

    Follow-on tissue-based treatment supports recovery, if medically appropriate.

  4. Follow-up & rehabilitation

    Rehabilitation and long-term follow-up make the result durable.

Established, innovative, experimental

Not all treatments are equal

AAM prioritizes scientifically supported interventions and distinguishes established treatments from experimental approaches.

For every request, independent medical reviewers determine whether the treatment is established, innovative or experimental, and what level of expertise and infrastructure it requires.

  • Established — standard of care with robust supporting evidence.
  • Innovative / validated — supported by evidence and available through recognized pathways.
  • Experimental — considered only with additional medical, ethical and regulatory review, including a check of appropriate clinical-trial options.

Does your situation fall within these domains?

Check our eligibility criteria.